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Tuesday, August 4, 2015SCCS

A163: Opinion of the SCCS

© CosmeticOBS-L'Observatoire des Cosmétiques

On June 25, 2015, during its 10th plenary meeting, the SCCS has adopted its Opinion on the hair dye cosmetic ingredient 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate (A163). This Opinion is open for comments until September 17, 2015.

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Background

It is the first submission on this new ingredient planned to be used as an oxidative hair colouring agent (precursor) in oxidative hair dye formulations at a maximum on-head concentration of 1.0%.

For exhaustive background information, see the article
SCCS: 4 requests for scientific Opinions (June 30, 2014)

Opinion

 1. In light of the data provided, does the SCCS consider 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate (A163) safe when used as an oxidative hair colouring agent (precursor) in oxidative hair dye formulations at a maximum on-head concentration of 1.0%?

The SCCS is of the opinion that 1-Hexyl 4,5-diamine pyrazole sulfate is safe for use in oxidative hair dye formulations with an on-head concentration of maximum 1.0% taken into account the scientific data provided.

 2. Does the SCCS have any further scientific concerns with regard to the use of 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate (A163) in cosmetic products?

 1-Hexyl 4,5-diamine pyrazole sulfate is a moderate skin sensitiser.

Deadline for comments

 17 September 2015.

Further information
• Full text of Opinion on A163, 25 June 2015, SCCS/1562/15

© CosmeticOBS-L'Observatoire des Cosmétiques

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