Monday, March 1, 2021Ingredients news

SantEnergy by Mibelle: energizing hair follicles

SantEnergy de Mibelle : le booster des follicules pileux

SantEnergy, the latest cosmetic active ingredient from the Swiss group Mibelle Biochemistry, is a polyphenol-rich extract sustainably obtained from the aerial parts of the plant Yerba Santa. It delays the ageing of hair follicles and increases both hair growth and hair density.

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Known as “mountain balm” and “holy herb”, Yerba Santa (Eriodictyon californicum) is a member of the Borage family (Boraginaceae) and it is native to the Pacific Coast of North America, especially California. The leaves of this plant have traditionally been used to treat upper respiratory infections and asthma.
Antioxidant, anti-inflammatory, anti-bacterial, and neuro-protective benefits of this plant have been reported in literature. Most of these health benefits were attributed to specific polyphenolic compounds present in the plant, such as homoeriodictyol, eriodictyol, and sterubin. Due to these antioxidant molecules, Yerba Santa is the perfect source for an active ingredient that protects hair follicles from ROS.

In vitro efficacy

• Caffeine-like invigorating and energizing effect
• Antioxidant activity inside the cell and at the cellular membrane
• Prevention of UV-induced DNA damage in the hair follicle
• Protection from UV-induced ROS (Nrf2 inactivation) in the hair follicle
• Delay of hair follicle aging
• Protection from premature hair follicle aging

In vivo efficacy

• Increase of anagen hair by 31.8%
• Decrease of telogen hair by -20.0%
• Increase in hair density by 13.1%

Technical data

• Charateristics: Water-soluble liquid, without preservatives
• Recommended use level: 1-2%
• Incorporation: For cold processes, …

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