Thursday, February 28, 2013Scientific publications

Methoxy PEG-22/Dodecyl Glycol Copolymer: a case of acute dermatitis


A publication of Lille (France) dermatologists repots the case of an acute allergic contact dermatitis due to Methoxy PEG-22/Dodecyl Glycol Copolymer present in a cosmetic cold cream, on a 6-year-old girl. The details of this case is published in the Annales de Dermatologie et de Vénéréologie (Annals of Dermatology and Venereology).

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A 6-year-old girl was referred with acute eczema of the face occurring within 12 h of applying a new moisturizing cream, "Mustela Cold Cream Nutriprotecteur". Patch tests were performed on the upper back using the Finn Chamber technique with the European standard series and the patient's own cream. Readings were performed after 2 days and the sole positive ++ reaction was associated with Mustela Cold Cream. Additional patch testing was carried out with the ingredients of the cream, with the sole positive ++ reaction again being to Methoxy PEG-22/Dodecyl Glycol Copolymer. The other ingredients were negative.

Methoxy PEG-22/Dodecyl Glycol Copolymer  is a copolymer used in cosmetics as an emulsion stabilizer and viscosity-increasing agent. It is found in 20 cosmetics currently on the market, most of which are prescribed for children.
Although it is rare, doctors must be aware of allergic contact dermatitis due to methoxy PEG 22 dodecyl glycol because of the extent of clinical reactions and because it chiefly affects the paediatric population.

The full publication is available on the Science Direct website for 31.50 dollars.

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