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Monday, September 20, 2021Ingredients

Zanthalene by Givaudan: a comforting phyto-botox active ingredient

Zanthalene de Givaudan : un actif phyto-botox réconfortant

Crafted by green fractionation, Zanthalene is a scalable natural active ingredient with botox-like efficacy and skin sensitivity modulation benefits. Created from Zanthoxylum bungeanum, commonly known as Sichuan pepper, Zanthalene is a cosmetic ingredient derived from spice and able to act on neuromuscular communication within the skin structure, providing well-ageing effects and soothing benefits depending on its concentratoin in formulas.

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All consumers eventually experience the effects of ageing on the skin, such as wrinkles and sensitivity. However, a large number will not be motivated to reverse these effects through invasive treatments. According to a study conducted online in May 2021 by Givaudan, 86% of consumers are currently interested in beauty products containing natural ingredients that help soothe skin discomfort while smoothing for a botox-like effect.
Giada Maramaldi, Personal Care Category Manager, Givaudan said: “Each facial expression activates a large number of muscles. With time and the decrease of collagen production, these expressions become even more marked and embedded on the skin, leading to the formation of wrinkles. In order to fight against these effects, Zanthalene offers a neurocosmetic strategy, enabling facial muscle relaxation in a safe, reversible and natural way, adding a sensation of comfort while removing skin discomfort.”

A progressive neurotransmission inhibitor

Zanthalene naturally contains α-hydroxy-sanshool, offering a specific solution to control skin nerves in a reversible way. It acts on specific neuron receptors, depleting the neurotransmitter thus inducing a status of numbness in three steps.
It induces a tingling sensation by stimulating various skin receptors (the “chemestesis” effect of spices) giving an immediate perception of activity to consumers; …

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