Tuesday, May 19, 2020Ingredients news

Silab's Agreynist: a repigmenting active to fight against grey hair

Agreynist de Silab : un repigmentant anti-cheveux gris

The ingredients supplier Silab presents its latest natural active ingredient Agreynist®, designed to foil the natural processes of hair greying. It is an anti-free radical and pro-pigmenting active ingredient of plant origin, enabling greying hair to return to its natural color without the need of dyeing it.

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Greying of hair is an unavoidable phenomenon, however, there is a strong consumer expectation to avoid it with natural solutions. Faced with this observation, Silab developed Agreynist®, a natural active ingredient capable of regulating the biological pathways leading to greying, in particular:
• It restores the oxidative balance of hair, a necessary factor of any anti-greying strategy, not only by reducing the formation of free radicals, but also by activating cell detoxification induced by autophagy
• It favors repigmentation of the hair fiber by stimulating the synthesis of melanin with its cytoprotective effect
• It re-establishes the structural quality of hair (result from an original modeling study*).
*Using Raman microspectroscopy, SILAB conducted a more detailed analysis of the course of greying and, in a novel way, has shown that there are changes in molecular markers related to biomechanical properties (conformation of proteins) and to the barrier function (organization of lipids) in grey hair.

A repigmenting effect

The repigmenting effect of Agreynist® was demonstrated on Caucasian and Asian, male and female volunteers.
A visual scoring by experts on photos highlighted that after four months of daily application, Agreynist® formulated at 2.5% in a lotion significantly decreases the …

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