The European Chemicals Agency (ECHA) has just announced that it has received two proposals for harmonised classification and labelling (CLH) for substances that can be used in cosmetics: Bronopol (a preservative) and Aminomethyl propanol (a pH regulator). If the classification process is completed, the latter could see its authorisation for use in cosmetic products called into question.
Bronopol
Identification
• CAS: 52-51-7
• EC: 200-143-0
INCI name
• 2-Bromo-2-Nitropropane-1,3-Diol
CosIng function
• Preservative
Cosmetics Regulation 1223/2009
• Currently listed in Annex V/21: concentration limited to 0.1%, the formation of nitrosamines must be avoided
CLP Regulation 1272/2008
Currently listed in Annex VI/603-085-00-8, with the following classifications:
• Acute Tox. 4*, H302 - Harmful if swallowed
• Acute Tox. 4*, H312 - Harmful in contact with skin
• Skin Irrit. 2, H315 - Causes skin irritation
• Eye Dam. 1, H318 - Causes serious eye damage
• STOT SE 3, H335 - May cause respiratory irritation
• Aquatic Acute 1, H400 - Very toxic to aquatic life, M-factor=10
Classification intention of Spain
• Acute Tox. 3, H301 - Toxic if swallowed
• Acute Tox. 4, H312 - Harmful in contact with skin
• Acute Tox. 3, H331 - Toxic if inhaled
• Skin Irrit. 2, H315 - Causes skin irritation
• Eye Dam. 1, H318 - Causes serious eye damage
• STOT SE 3, H335 - May cause respiratory irritation
• Aquatic Acute 1, H400 - Very toxic to aquatic life, M-factor=10
• Aquatic Chronic 1, H410 - Very toxic to aquatic life with long lasting effects, M-factor=10
