Basic Brown 16, 4-Amino-2-nitrodiphenylamine-2’-carboxylic acid, Acid Black 1, 5-amino-6-chloro-o-cresol, and the new 2-Methoxy-methyl-p-phenylenediamine: five hair dyes are today the topic of request for opinion by the SCCS. (Article updated on 21 October)
Basic Brown 16
Th SCCP (ex-SCCS) already issued an opinion on Basic Brown 16 (CAS: 26381-41-9) in 2008, with the conclusions that some aspect related to the
genotoxicity potential of this ingredient needed clarification.
The purpose of the present submission, submitted by Cosmetics Europe in April 2012, is to describe the results of two in vitro genotoxicity studies together with a safety assessment for the use of this ingredient.
The SCCS is asked today to answer the following questions:
1. Does the SCCS consider Basic Brown 16 safe for use as a non-oxidative hair dye with an on-head concentration of maximum 2.0 % taken into account the scientific data provided?
2. Does the SCCS recommend any restrictions with regard to the use of Basic Brown 16 in non-oxidative hair dye formulations?
4-Amino-2-nitrodiphenylamine-2’-carboxylic Acid
4-Amino-2-nitrodiphenylamine-2’-carboxylic Acid (CAS: 117907-43-4) is used as a direct dye in hair dye formulations or as an ingredient in oxidative dying products which may or may not contain a hydrogen peroxide based developer mix up to a final concentration of 2.0% on head.
The SCCS issued an opinion in March 2011 with the conclusions that some aspect related to the genotoxicity potential of this ingredient needed clarification. …
