The notification letter is dated 30 June 2023, and this date opens the deadline for the new provisions to come into force. A total of 59 fragrance substances are affected by this 51st amendment to the IFRA (International Fragrance Association) Standards, which also includes a number of interpretative clarifications for their use.
The new Standards
So there are 59 new features on the programme for this 51st amendment.
1 new prohibition Standard
• 3-Acetyl-2,5-dimethylfuran (CAS: 10599-70-9)
1 new specification Standard
• Allyl-3-cyclohexylpropionate (CAS: 2705-87-5; INCI : Allyl Cyclohexylpropionate)
46 new restriction Standards
32 based on dermal sensitization and systemic toxicity
• 4-tert-Butylcyclohexanone (CAS: 98-53-3; INCI: 4-Tert-Butylcyclohexanone)
• 2-tert-Butylcyclohexanone (CAS: 1728-46-7; INCI: 2-Tert-Butylcyclohexanone)
• 1-(2-tert.-Butyl cyclohexyloxy)-2-butanol (CAS: 139504-68-0; INCI: 2-T-Butylcyclohexyloxybutanol)
• Carvomenthone (CAS: 499-70-7 / 59471-80-6; INCI : Isopropyl-Methylcyclohexanone)
• Citronellyl acetate (CAS: 150-84-5 / 67601-05-2 / 141-11-7; INCI: Citronellyl Acetate / Rhodinyl Acetate)
• Cyclohexadecanone (CAS: 2550-52-9)
• Cyclohexadecenone (CAS: 88642-03-9 / 5365-06-0 / 2550-59-6 / 3100-36-5 / 5120-20-7 / 854373-71-0 / 854373-70-9; INCI: 8-Cyclohexadecenone)
• alpha-Cyclohexylidene benzeneacetonitrile (CAS: 10461-98-0)
• 2-Cyclohexylidene-2-ortho-tolylacetonitrile (CAS: 916887-53-1)
• Dimethyl octenone (CAS: 2550-11-0; INCI: 4,7-Dimethyl-6-Octen-3-One)
• (Ethoxymethoxy)-cyclododecane (CAS: 58567-11-6; INCI: Formaldehyde Cyclodecyl Ethyl Acetal)
• Ethyl and Methyl furaneol (CAS: 27538-09-6 / 27538-10-9; INC : 5-Ethyl-4-Hydroxy-2-Methylfuran-3(2H)-One)
• Ethyl isopropyl bicycloheptene-2-carboxylate (CAS: 116044-44-1 / 116126-82-0; INCI: Ethyl Isopropyl-Bicycloheptene-2-Carboxylate)
• cis-3-Heptenyl acetate (CAS: 1576-78-9; INC : Cis-3-Heptenyl Acetate)
• cis-3-Hexenyl isovalerate (CAS: 35154-45-1; INCI: Cis-3-Hexenyl Isovalerate)
• cis-3-Hexenyl methyl carbonate (CAS: 67633-96-9; INCI: Cis-3-Hexenyl Methyl …
