During its meeting on December 16, 2014, the SCCS has adopted its Opinion on Basic Blue 124, published an addendum to its conclusions on Ethyl lauroyl arginate HCl and revised its Opinions on Polyaminopropyl biguanide and Formaldehyde in nail hardeners. It also revised its clarification on the meaning of the term 'sprayable'.
Basic Blue 124
Background
The new ingredient Basic Blue 124 is intended to be used as a direct hair dye in semi-permanent as well as in permanent (oxidative) hair dye formulations at on-head concentrations in the range between 0.01% up to a maximum of 0.5% (w/v). The regular frequency of application is intended to be once per month up to once per 8 weeks.
For exhaustive background information, see the article
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SCCS: 4 requests for scientific Opinions
(June 26, 2014)
Opinion
1. In light of the data provided, does the SCCS consider Basic Blue 124 safe when used as a direct hair dye in semi-permanent as well as in permanent (oxidative) hair dye formulations at on-head concentration up to a maximum of 0.5% (w/v)?
The safety of Basic Blue 124 cannot be assessed since no final conclusion on mutagenicity can be drawn without further studies to exclude gene mutation potential.
2. Does the SCCS have any further scientific concerns with regard to the use of Basic Blue 124 in cosmetic products?
The SCCS considers Basic Blue 124 a strong skin sensitiser. Basic Blue 124 is a tertiary amine. It should not be used together with nitrosating agents. Total nitrosamine …
