The SCCS has just published its Opinion on the safety of two hair dye ingredients, Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165). This Opinion has been adopted during the plenary meeting of 20-21 June 2019, and is opened to comments until 9 September 2019.
Background
The ingredients Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165) are intended to be used in oxidative hair colouring products up to a maximum on-head concentration of 2%.
For an exhaustive background information, see the article
• Hydroxypropyl p-phenylenediamine and its dihydrochloride salt: Request for Opinion to SCCS, CosmeticOBS, 7 November 2017
Opinion
1. In light of the data provided, does the SCCS consider Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165), safe when used in oxidative hair colouring products up to a maximum on-head concentration of 2 %?
In light of the data provided, the SCCS considers that Hydroxypropyl p-Phenylenediamine and its dihydrochloride salt are not safe due to potential genotoxicity when used in oxidative hair colouring products up to a maximum on-head concentration of 2%.
2. Does the SCCS have any further scientific concerns with regard to the use of Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165) in cosmetic products?
A mild to moderate eye irritation potential of the test item cannot be excluded. Hydroxypropyl p-phenylenediamine 2HCl is a moderate skin sensitiser based on animal data.
For further information
• See the full text of SCCS (Scientific Committee on Consumer Safety), Opinion on 38 Hydroxypropyl p-phenylenediamine and its …
