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Wednesday, April 22, 2015SCCS

SCCS: Opinion on Cetylpyridinium chloride

© CosmeticOBS-L'Observatoire des Cosmétiques

During its plenary meeting on March 25, 2015, the SCCS has adopted its Opinion on the new preservative Cetylpyridinium chloride. This Opinion is open for comments until May 29, 2015.

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In 2006, a first Opinion on Cetylpyridinium chloride was published with the following conclusion:
" In view of the poor quality of the toxicological data presented in the current dossier, the SCCP requires a new dossier to be submitted in which data is provided to all relevant toxicological end-points and conforming to currently accepted standards. "

A 2nd submission was submitted in July 2011 by Cosmetics Europe supplemented by separately submitted company data.

For exhaustive background information, see the article
SCCS: Soon-to-be-released opinions on two new preservatives (December 4, 2013).


 1. On the basis of the data provided, does the SCCS consider that Cetylpyridinium chloride is safe for consumers, when used as a preservative in cosmetic products in the following specified concentrations:
• mouthwashes cosmetic products up to a concentration of 0.1%
• all other oral hygiene cosmetic products up to a concentration of 0.5%
• skin lotions and creams up to a concentration of 0.2%
• anti-perspirant deodorants up to a concentration of 20 %

Except for potential skin, eye and oral mucosal irritation, the SCCS considers that the use of Cetylpyridinium chloride in a single cosmetic product for oral and for dermal application is safe …

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