4-hydroxy-4-methylpentan-2-one (CAS No.123-42-2, EC No.204-626-7, INCI: Diacetone Alcohol) is an ingredient listed in the Cosing, with the functions: Fragrance, Solvent.
The substance is currently not regulated by the European Cosmetics Regulation 1223/2009.
It is already listed in Annex VI/603-016-00-1 of the European CLP Regulation 1272/2008, with the following classification:
• Eye Irrit. 2, H319 - Causes serious eye irritation (Specific concentration limit: C ≥ 10%).

France proposes the following classification.

Identification
Index number
• 603-016-00-1
Chemical name
• 4-hydroxy-4-methylpentan-2-one; diacetone alcohol
EC number
• 204-626-7
CAS number
• 123-42-2
Classification
Hazard class and Category code(s)
• Eye Irrit. 2
• Repr. 1B
Hazard statement code(s)
• H319 - Causes serious eye irritation
• H360D - May damage the unborn child
Labelling
Pictogram, Signal word code(s)
• GHS07
• GHS08
• Dgr (Danger)
Hazard statement code(s)
• H360D - May damage the unborn child
Specific concentration Limits, M-factors and ATE
• Eye Irrit. 2; H319: C ≥ 10 %

This consultation is open until 18 October 2024.
If the classification process comes to an end and this substance actually become Repr. 1B, it could be listed as CMR and its use could …