Tuesday, April 20, 2021European Commission

Methyl-n-Methylanthranilate: forthcoming restrictions notified by Europe to the WTO

Methyl-n-Methylanthranilate : prochaines restrictions notifiées par l'Europe à l'OMC

On 15 March 2021, the European Union transmitted to the WTO a draft Regulation intended to introduce restrictions on the use of the fragrance ingredient Methyl-n-Methylanthranilate. Amendments to Annexe III (restricted substances) to the Cosmetics Regulation 1223/2009 are expected to be adopted in the 3rd quarter of 2021.

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Notification Date

15 March 2021

Products covered

Cosmetic products; Cosmetics. Toiletries (ICS 71.100.70)

Title of the notified document

Draft Commission Regulation amending Regulation (EC) No.1223/2009 of the European Parliament and of the Council as regards the use of Methyl-n-Methylanthranilate in cosmetic products


This draft Commission Regulation would restrict the use of the substance Methyl-n-Methylanthranilate (M-N-MA) in the following ways: M-N-MA content should be limited to maximum 0.1% for leave-on and 0.2% for rinse-off cosmetic products; the use of M-N-MA with nitrosating agents should be banned; the maximum nitrosamine content should be restricted to 50 μg/kg both for leave-on and rinse-off products; M-N-MA should not be used in leave-on sunscreen products and products marketed for exposure to natural/artificial UV light; products containing M-N-MA should be kept in nitrite-free containers.


Protection of human health or safety

The text of the future regulation


  1. The substance Methyl-n-Methylanthranilate (M-N-MA) (CAS No.85-91-6) is a fragrance ingredient used in various cosmetics, including fine fragrances, shampoos, soaps and other toiletries. M-N-MA is currently not subject to any prohibition or restriction pursuant to Regulation (EC) No.1223/2009.

  2. The Scientific Committee on Consumer Safety (SCCS) concluded in an Opinion adopted at its plenary meeting of 13-14 December 2011 …

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