Exclusively developed by Bio Genetic Technology, the Cybelle™ System mirrors the AI architecture utilized by AIGC, making it the first AIGC protein generation evolution system to be commercialized in the professional field.

Through sequence optimization by our AIGC protein generation evolution design platform, BGT™ TDP-1 is an innovative cosmetic polypeptide designed for instant anti-wrinkle effects; it has been clinically proven to reduce wrinkles rapidly within 15 minutes of application, and to deliver significant long-term skin smoothing and anti-wrinkle benefits.

BGT™ TDP-1, Tridecapeptide-1, represents a revolutionary breakthrough in anti-aging peptide technology. It targets wrinkle formation directly and quickly diminishes fine lines and wrinkles. We are ushering in a new era of anti-aging skincare, where science and innovation converge for healthier, smoother, and more beautiful skin. The heart of our advancement, the Cybelle™ System, underscores our commitment to cutting-edge technology and ensures unparalleled efficacy in our skincare solutions.

Mechanism of Action:

Unlike any other cosmetic anti-wrinkle polypeptides, this novel polypeptide specifically targets the neuronal nicotinic acetylcholine receptor (nAChR), focusing on the α and σ subunits. By inhibiting acetylcholine binding to nAChR, it disrupts the neurological communication responsible for muscle contraction signals. BGT™ TDP-1 quickly penetrates the skin, effectively binding to the acetylcholine receptor (nAChR) and inhibiting acetylcholine (ACh) function. This regulation of muscle contraction results in the removal of wrinkles, achieving unprecedented anti-aging effects.

Clinical Testing Results:

Testing Subjects IN-VIVO :

Age: 30-60 years old
Gender: female
Number of evaluators: 35 people

Testing Method:

Apply 0.3gr of the anti-wrinkle essence to the corner of the right eye and determine the wrinkle volume and skin roughness after application for 15 minutes, 1 hour, 2 hours, 4 hours; continuous for 2 weeks, 4 weeks (once a day in the morning and evening).

Evaluation of Wrinkle Reduction Effect:

Consumers have observed a noticeable reduction in fine lines around the eye corners just 15 minutes after use, with no rebound of these lines until the fourth hour. Additionally, skin smoothens significantly improves after 15 minutes and remains largely unchanged for 4 hours.

Instant Wrinkle Reduction:

The immediate wrinkle-reducing effect of BGT™ TDP-1 intensifies with higher concentrations. At 1-3% usage, approximately 25-40% of consumers notice wrinkle reduction within 1(minutes to 1 hour after application. However, 90% of consumers noticed wrinkle reduction at 10% usage.

Long-Term wrinkle Reduction:

The long-term wrinkle-reduction effects of BGT™ TDP-1 are evident even at lower concentrations. At 3%, 6% and 10% concentrations, all users experienced a 100% reduction in wrinkles and significant skin improvement after 4 weeks of use.

Conclusion:

In conclusion, the Cybelle™ system, developed exclusively by Bio Genetic Technology, represents a groundbreaking advancement for the cosmetics industry. As a pioneer in the commercialization of AIGC, it has paved the way for innovative solutions in anti-aging care. At the forefront of this innovation is BGT™ TDP-1, a revolutionary cosmetic polypeptide that combines immediate effectiveness with long-term benefits, offering rapid wrinkle reduction and lasting smoothing effects for the skin. This innovation is available to formulators through DKSH France, the exclusive distribution partner of BGT. Among its recent prototypes, Performer’s Secret, an anti-aging formula combining BGT™ TDP-1 and BGT ALP, was a finalist in the top 15 at the 2025 Cosmet’Agora Formulation Awards. Discover this revolutionary polypeptide and the complete range of BGT products on the platform https://www.dkshdiscover.com