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Summer 2022 special
Friday, July 22, 2022Regulation

Endocrine disruptors: 2nd OPSS call for data

Perturbateurs endocriniens : 2e appel à données de l'OPSS

The Office for Product Safety and Standards (OPSS), which regulates cosmetic products in the UK, has launched a call for data for six ingredients with endocrine disrupting properties, in order to assess their safety. A first call for data had already been launched on 5 April for five other substances.

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This call for evidence targets six cosmetic ingredients
• Propylparaben (CAS 94-13-3)
• Resorcinol (CAS 108-46-3)
• Benzophenone (CAS 119-61-9)
• Benzyl salicylate (CAS 118-58-1)
• Genistein (CAS 446-72-0)
• Daidzein (CAS 486-66-8)
It runs until 30 September 2022.

These six ingredients have also been the subject of a call for data by the European Commission and mandates to the SCCS.
The Scientific Committee has already published its final Opinions on Propylparaben and Resorcinol, and a preliminary Opinion on Genistein and Daidzein.
The safety assessment of Benzyl salicylate is still ongoing.
As for Benzophenone, it has been removed from the process, the European industry having decided not to submit a dossier in defence of the substance, while the 18th ATP (Adaptation to Technical and Scientific Progress) of the CLP (Classification, Labelling and Packaging of Substances) Regulation 1272/2008, published on 3 May 2022, puts it in Annex VI, with a classification as a category 1B carcinogen. There is therefore almost no doubt that it will be banned for use in cosmetics, pursuant to Article 15 of Regulation 1223/2009.

The first OPSS call for data for endocrine disruptors concerned Benzophenone-3 (CAS 131-57-7), Octocrylene (CAS 6197-30-4), Homosalate (CAS 118-56-9), Kojic acid …

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