They have been adopted during the 17th plenary meeting, on 11 December, 2012, and are open for comments until 1st February, 2013. The SCCS has just released five new opinions on hair dyes.
1,2,4-Trihydroxybenzene
On 18 March 2006, the SCCS have already published an Opinion on 1,2,4-Trihydroxybenzene, with the conclusion that the information submitted by the industry was inadequate to assess the safe use of the substance. SCCS required more information for any further consideration. The current Opinion is based on the new data provided by the industry.
Once again, the SCCS is "
of the opinion that the information submitted is inadequate to assess the safe use of the substance
".
Before any further consideration, the following information is required:
• Proper characterisation and quantification of 1,2,4-Trihydroxybenzene as well as identification and quantification of impurities in all test batches.
• Characterisation of the oxidation reaction product(s) of 1,2,4-trihydroxybenzene to which the consumer is exposed, because of the reported instability of 1,2,4- trihydroxybenzene in aqueous systems. In the case of relevant exposure to the reaction products, further toxicity data might be required.
•
In vivo
testing would be required to explore the potential to induce gene mutations; such tests are no longer permitted.
1,2,4-Trihydroxybenzene was found to be an extreme skin sensitiser.
• See the full text of SCCS opinion
5-Amino-6-chloro-o-cresol
In 2009, the SCCS expressed its Opinion on 5-Amino-6-chloro-o-cresol with the following …
