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Monday, January 20, 2025Ingredients

Formyl Morpholine, Dimethylaminopropylamine, Hydroxycitronellal: CLH classification proposals

Formyl morpholine, Dimethylaminopropylamine, Hydroxycitronellal : propositions de classifications CLH

On 15 January 2025, the European Chemicals Agency (ECHA) published proposals for harmonised classification and labelling (CLH) for three ingredients that may be used in cosmetics: Formyl Morpholine, Dimethylaminopropylamine and Hydroxycitronellal.

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Formyl morpholine

4-morpholinecarbaldehyde (CAS No.4394-85-8, CE No.224-518-3, INCI: Formyl Morpholine) is an ingredient listed in the Cosing, with the function: Solvent.
The substance is not currently regulated by European Cosmetics Regulation 1223/2009, nor is it listed in Annex VI of European CLP Regulation 1272/2008.

Belgium proposes to classify the substance as follows:
• Skin Sens. 1B, H317 - May cause an allergic skin reaction.

Dimethylaminopropylamine

3-aminopropyldimethylamine (CAS No.109-55-7, EC No.203-680-9, INCI: Dimethylaminopropylamine) is an ingredient listed in the Cosing, with no function reported.
The substance is included in Annex III/62 of the European Cosmetics Regulation 1223/2009, which limits trialkylamines, trialkanolamines and their salts to 2.5% in leave-on products, and details theconditions of use in order to prevent nitrosation phenomena.
It is also listed in Annex VI/612-061-00-6 of European CLP Regulation 1272/2008, with the following classifications:
• Flam. Liq. 3, H226 - Flammable liquid and vapour
• Acute Tox. 4 (*), H302 - Harmful if swallowed
• Skin Corr. 1B, H314 - Causes severe skin burns and eye damage
• Skin Sens. 1, H317 - May cause an allergic skin reaction

Austria proposes to classify the substance as follows:
• Flam. Liq. 3, H226 - Flammable liquid and vapour …

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